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This is more of a funny question to think about, but I am wondering, theoretically if it is possible in cells to synthesize nucleic acids(DNA, RNA) from proteins. What might this be useful for and how could it be working?

User Sunefred
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Final answer:

The concept of synthesizing nucleic acids from proteins in cells is not a standard process and reverses the flow of genetic information in known biological systems. The RNA world hypothesis offers a theoretical framework where RNA, not DNA, acts as the first genetic material that both stores information and catalyzes its own replication. While the idea is intriguing and touches upon the origins of life, no natural mechanism exists for protein-to-nucleic acid synthesis.

Step-by-step explanation:

Theoretically, synthesizing nucleic acids (DNA, RNA) from proteins in cells is not standard in current biological processes, as it reverses the central dogma of molecular biology where information flows from DNA to RNA to proteins. However, exploring such a reversal touches on origins of life research where the RNA world hypothesis places RNA as a central figure capable of both storing genetic information and catalyzing reactions before DNA and proteins became predominant. The RNA world suggests that RNA could replicate itself and facilitate the synthesis of proteins.

The experiment by Nirenberg and Matthaei showed that synthetic RNA can direct the assembly of specific polypeptides, which demonstrates how RNA can dictate protein formation. Applied to early life forms, an RNA world could have gradually transitioned into the modern biology paradigm we see today, where DNA is the genetic material, and proteins are the workhorses of the cell.

If cells or prebiotic chemical systems found a way to synthesize nucleic acids from proteins, it could revolutionize our understanding of molecular evolution and the origin of life. However, such a process is purely speculative and currently has no known mechanism within biological systems.

User Serge Rogatch
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