Question

Which of the following is a genetic disease that results in almost no adaptive immunity due to lack of B and/or T cells?

a) Ataxia-telangiectasia
b) Wiskott-Aldrich syndrome
c) Chronic granulomatous disease
d) X-linked severe combined immunodeficiency (X-SCID)

Answer 1

X-linked severe combined immunodeficiency (X-SCID) is a genetic disease that results in almost no adaptive immunity due to a lack of B and/or T cells. Patients with X-SCID have defects in both the B cell and T cell arms of the adaptive immune response, impairing the body's ability to mount an effective immune response.d) X-linked severe combined immunodeficiency (X-SCID)

Step-by-step explanation:

X-linked severe combined immunodeficiency (X-SCID) is a genetic disease that results in almost no adaptive immunity due to a lack of B and/or T cells. Patients with X-SCID have defects in both the B cell and T cell arms of the adaptive immune response, impairing T-cell dependent antibody responses as well as cell-mediated immune responses. As a result, patients with X-SCID cannot develop immunological memory and vaccines do not provide them with protection.