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Gait abnormality, slow movement, asymmetric UE rigidity. Difficulty in voluntary vertical upward/downward gaze. Slowness/rigidity improved slightly with levodopa. Later has problems with horizontal&vertical gaze. Oculocephalic reflexes normal.

User FourwingsY
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Final answer:

The symptoms described, such as gait abnormality, difficulty with gaze, and unilateral rigidity, could point towards a complex movement disorder like progressive supranuclear palsy, ataxia, or Parkinson's disease with additional complications affecting eye movements.

Step-by-step explanation:

The scenario described suggests a neurological condition affecting movement and eye function. While the initial symptoms of gait abnormality, slow movement, and unilateral upper extremity (UE) rigidity might suggest Parkinson's disease, improvement with levodopa and significant difficulty in voluntary vertical and horizontal gaze points towards a more complex movement disorder. Parkinson's is characterized by distinct motor signs including muscle tremor, muscle rigidity, slowness of movement, and postural instability. The dysfunction in vertical and horizontal gaze, however, may imply a condition like progressive supranuclear palsy (PSP), which often has overlapping features with Parkinson's but is notable for its distinctive eye movement problems.

Furthermore, the description of consecutive problems with horizontal and vertical gaze and normal oculocephalic reflexes indicates the possibility of a condition affecting the areas responsible for eye movements, such as the brainstem, cerebellum, or related pathways. Internuclear ophthalmoplegia, for example, can cause diplopia (double vision) due to failure of coordination between the eyes during lateral gaze. It's also important to consider ataxia, a movement disorder of the cerebellum causing loss of coordination in voluntary movements, which can lead to gait and balance issues.

User Vertex
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