Final answer:
In systemic lupus erythematosus (SLE), lupus antibodies are associated with renal disease.
Step-by-step explanation:
In systemic lupus erythematosus (SLE), there is an association between lupus antibodies and renal disease. SLE is an autoimmune disease where the immune system produces autoantibodies that target the body's own DNA and proteins. These autoantibodies, such as antinuclear antibodies (ANAs) and anti-double-stranded DNA (ds-DNA) antibodies, can cause inflammation and damage in various organs, including the kidneys. The presence of these lupus antibodies is important in the diagnosis and classification of SLE.