Final answer:
Mebendazole, thiabendazole, and ivermectin are drugs used to treat parasitic infections. Mebendazole and thiabendazole are synthetic benzimidazoles that inhibit microtubule formation in helminths, while ivermectin inhibits neuronal transmission in helminths.
Step-by-step explanation:
Mebendazole, thiabendazole, and ivermectin are drugs used to treat parasitic infections.
Mebendazole and thiabendazole are synthetic benzimidazoles that bind to helminthic ß-tubulin, preventing microtubule formation. This leads to a reduction in glucose uptake in the intestinal cells of the worms, resulting in their death. They are effective against a broad range of helminths, protozoans, fungi, and viruses.
Ivermectin belongs to the avermectins drug class and specifically inhibits neuronal transmission in helminths. It is used to treat roundworm diseases, river blindness, strongyloidiasis, and parasitic insect infestations.