Final answer:
The nurse should instruct the patient to fast overnight before the 3-hour oral glucose tolerance test to ensure accurate results.
Step-by-step explanation:
The nurse should give the instruction to fast overnight before the test. A glucose tolerance test measures the body's ability to process glucose and detect diabetes. Fasting overnight helps ensure accurate measurements of blood glucose levels, as eating or drinking can affect the results. By fasting, the patient will have an empty stomach, allowing for accurate assessment of glucose tolerance.