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What are adverse effects of amitriptyline (anticholinergic effects)?

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Final answer:

Amitriptyline is a tricyclic antidepressant that can cause a range of anticholinergic side effects including blurred vision, constipation, and more severe symptoms affecting heart function and muscle coordination in serious cases.

Step-by-step explanation:

Amitriptyline is a tricyclic antidepressant with anticholinergic effects that can lead to several adverse reactions. The anticholinergic effects include symptoms such as blurred vision, constipation, dry mouth, urinary retention, and in severe cases, effects on heart function and muscle coordination. Other known side effects of this medication include weight gain, fatigue, loss of sexual desire, agitation, insomnia, nausea, and light sensitivity.

Anticholinergic Effects

The anticholinergic side effects from amitriptyline can be quite serious, specifically for elderly patients or those with preexisting conditions. Symptoms such as miosis (pinpoint pupils), blurred or dim vision, muscle twitching or fasciculations, seizures, and even unconsciousness can occur. These effects are due to the medicine hindering the activity of the neurotransmitter acetylcholine, which is responsible for many functions in the body, including muscle movement and autonomic nervous system responses.

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