Final answer:
Epigenetic modifications are important for deciding treatment options for different tumors because they affect transcription patterns. One key epigenetic modification is histone acetylation, which can alter gene expression and contribute to the development of tumors.
Step-by-step explanation:
The correct answer is b) Epigenetic modifications.
Different tumors have different transcription patterns, and these patterns are controlled by various factors. One of the key factors that play a role in determining the transcription patterns of tumors is epigenetic modifications. Epigenetic modifications involve changes to the structure of DNA or the proteins associated with it, without altering the underlying DNA sequence. These modifications can affect gene expression and contribute to the development and progression of cancer.
For example, one important epigenetic modification is histone acetylation. Histones are proteins that help package DNA into a compact structure called chromatin. Acetylation of histones can loosen the structure of chromatin, making the DNA more accessible for transcription. Changes in histone acetylation can lead to altered gene expression and contribute to the development of tumors.