Final answer:
Tolerance is the correct answer. Physical withdrawal symptoms without the drug are associated with dependence, not tolerance.
Step-by-step explanation:
Tolerance is the correct answer.
Tolerance occurs when a drug user requires more and more of a given drug in order to experience the same effects of the drug. In the context of the question, physical withdrawal symptoms like alterations in heart rate or blood pressure without the drug are not associated with tolerance, but rather with dependence. Dependence involves changes in normal bodily functions and the user will experience withdrawal from the drug upon cessation of use.
Addiction is the compulsive use of a drug despite negative consequences, and abstinence refers to refraining from using a drug or substance.
Physical withdrawal symptoms may vary but typically include issues like tremors, pain, and seizures with certain substances. For instance, nicotine withdrawal can include symptoms such as cravings for nicotine, headaches, irritability, and changes in blood pressure. Facing these withdrawal symptoms without medical assistance can be dangerous, and substances like alcohol and barbiturates may necessitate medical supervision during the cessation process to manage the potential life-threatening symptoms.