Question

How do Cialis and Viagra work?

A) By increasing blood flow to the brain
B) By inhibiting phosphodiesterase-5 (PDE5)
C) By acting as beta-blockers
D) By enhancing insulin sensitivity

Answer 1

Cialis and Viagra work by inhibiting phosphodiesterase-5 (PDE5) in order to increase blood flow to the and promote an erection.

Step-by-step explanation:

Cialis and Viagra work by inhibiting phosphodiesterase-5 (PDE5). When the release of nitric oxide (NO) induces relaxation of the smooth muscles that surround the penile arteries, PDE5 degrades a key component of the NO signaling pathway, preventing vasodilation necessary for an erection. By inhibiting PDE5, blood flow is increased, allowing vasodilation of the to occur and promoting an erection.