Final answer:
Muscle weakness is the adverse effect of baclofen that the nurse should identify in a client with multiple sclerosis.
Step-by-step explanation:
The nurse should identify muscle weakness as an adverse effect of baclofen in a client with multiple sclerosis (MS). Baclofen is a medication used to relieve muscle spasticity, which is commonly prescribed for MS patients. While it is effective in reducing muscle rigidity and spasms, muscle weakness is a known side effect, as it can impair muscle strength by its action on the central nervous system. Baclofen does not commonly cause hypertension, bradycardia or increased appetite, so these would not be identified as typical adverse effects of this medication in relation to MS.