Final answer:
Ascorbic acid is necessary for the production of hydroxyproline, an integral part of the collagen structure that provides strength and rigidity to connective tissues. It acts as a cofactor for prolyl hydroxylase in the synthesis of hydroxyproline.
Step-by-step explanation:
Ascorbic acid is required for the production of hydroxyproline in collagen. This is essential because hydroxyproline is an important constituent of collagen, which is a protein that adds strength and rigidity to connective tissue structures including tendons, ligaments, and bones. The synthesis of hydroxyproline occurs through the hydroxylation of proline, a process catalyzed by prolyl hydroxylase, an enzyme which uses ascorbic acid as a cofactor. Without adequate availability of ascorbic acid, also known as vitamin C, collagen synthesis can be compromised, leading to conditions such as scurvy.
Additionally, the triple-helical structure of collagen comprises repeating sequences where hydroxyproline is often found. This amino acid is critical for the stability of the collagen triple helix, hence, the presence of ascorbic acid is critical for proper collagen formation.