Question

A 75-year-old patient, who has a history of postoperative delirium who will undergo coronary artery bypass surgery shortly. The most appropriate strategy to prevent postoperative delirium in this patient would be to start which of the following medications?

A. Lorazepam
B. Donepezil
C. Memantine
D. Sertraline
E. Start no new medication since pharmacologic strategies are not effective in preventing delirium

Answer 1

The most appropriate strategy to prevent postoperative delirium in a 75-year-old patient with a history of postoperative delirium who is about to undergo coronary artery bypass surgery would be to start no new medication.

Step-by-step explanation:

The most appropriate strategy to prevent postoperative delirium in a 75-year-old patient with a history of postoperative delirium who is about to undergo coronary artery bypass surgery would be to start no new medication. Pharmacologic strategies, including medications such as lorazepam, donepezil, memantine, and sertraline, have not been shown to be effective in preventing delirium in this context. Other non-pharmacologic strategies that have been used include managing underlying medical conditions, optimizing sleep, promoting mobility, and providing cognitive stimulation.