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What are the disadvantages of the Malloy & Evelyn method for bilirubin?

a) Low specificity, high cost, low sensitivity
b) Limited precision, time-consuming, requires specialized equipment
c) Inaccurate in the presence of hemolysis, costly reagents, lengthy procedure
d) Prone to contamination, poor reproducibility, operator-dependent

1 Answer

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Final answer:

The Malloy & Evelyn method for bilirubin measurement has disadvantages including low specificity, high cost, and low sensitivity.

Step-by-step explanation:

The Malloy & Evelyn method is used to measure bilirubin levels in the blood, which is important for diagnosing and monitoring liver diseases. However, this method has several disadvantages:

  1. Low specificity: The method may not accurately differentiate between direct and indirect bilirubin, leading to potential misinterpretation of results.
  2. High cost: The method requires specialized equipment and costly reagents, making it expensive to perform.
  3. Low sensitivity: The method may not be sensitive enough to detect low levels of bilirubin, leading to false-negative results.

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