Final answer:
The most important route by which pathogens are transmitted in health care settings including dialysis centers is Direct contact transmission.
Step-by-step explanation:
The most important route by which pathogens are transmitted in health care settings including dialysis centers is Direct contact transmission. This occurs when pathogens spread from person to person through direct contact between an infected person and a new host. It can happen through skin-to-skin contact, touching the same surfaces, or through oral contact such as kissing or sharing items that go in the mouth.