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What binds to the ORC (origin recognition complex) to assemble the prereplication complex (pre-RC) taht is competent to initiate replication?

User Kares
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Final answer:

The ORC binds to specific nucleotide sequences called origins of replication to assemble the pre-RC that is competent to initiate replication.

Step-by-step explanation:

The ORC (origin recognition complex) binds to specific nucleotide sequences called origins of replication to assemble the prereplication complex (pre-RC) that is competent to initiate replication. In prokaryotes, such as E.coli, the ORC recognizes the 245 base pair-long origin of replication, which is rich in adenine-thymine (AT) sequences. In eukaryotes, multiple origins of replication exist on the chromosome, and the ORC binds to these origins to initiate replication.

User Anhldbk
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