Final answer:
The two primary Dutch grievances leading to their revolt against Spanish rule were economic restrictions and religious persecution. These issues were at odds with the Netherlands' pursuit of religious liberty and commercial independence from Spanish mercantilist policies.
Step-by-step explanation:
The two primary grievances that provoked the Dutch revolt against Spanish rule in the late 16th century were economic restrictions and religious persecution. These issues stemmed from the Netherlands' desire for intellectual and religious freedom, which clashed with Spanish imperial policies and the enforcement of Catholicism.
The Dutch disliked the limitations placed upon their commercial activities due to Spain's mercantilist policies, and they resented the Spanish attempts to suppress Protestantism in favor of Catholic orthodoxy. This discontent led the Dutch to fight for and eventually gain independence from Spain, establishing a republic that promoted both religious tolerance and economic freedom.