Final answer:
The best way to determine if instruments are sterile is by using indicators such as autoclave tape and biological indicator spore tests. Autoclaves may also be equipped with recorders to document sterilization parameters.
Step-by-step explanation:
The best way to determine if instruments are sterile is by using indicators. There are different types of indicators used to ensure proper sterilization. One common type is autoclave tape, which turns black when the appropriate temperature is achieved during autoclaving. Another type is a biological indicator spore test, which uses heat-resistant endospores to determine if sterilization was successful. Additionally, autoclaves may be equipped with recorders to document the pressures and temperatures achieved during each run.