Final answer:
Transcription is activated when activators bind to enhancer regions on the DNA strand. This binding causes a shape change in the DNA, allowing for interaction with transcription factors and the initiation of transcription.
Step-by-step explanation:
Transcription is activated/induced when activators bind to enhancer regions on the DNA strand.
Enhancer regions are binding sequences for transcription factors, and when an activator protein binds to the enhancer, it causes a shape change in the DNA. This shape change allows for the interaction of the activators with transcription factors, which leads to the initiation of transcription by RNA polymerase.