Final answer:
Early detection is crucial in managing Alzheimer's disease, and some forms are hereditary due to specific genetic mutations. Treatments, such as cholinesterase inhibitors, aim to slow progression by enhancing acetylcholine neurotransmission. Opiate exposure is not a cause of AD, and it is not a congenital disease. option 2
Step-by-step explanation:
Among the statements provided about Alzheimer's disease (AD), early detection being critical for managing the progression of AD is true. Early detection methods, including the development of a blood test for early β-amyloid (Aβ) detection, may offer hope for future therapies to better manage the disease. Although there is no cure for Alzheimer's disease, some treatments aim to slow the progression by enhancing neurotransmission, such as using cholinesterase inhibitors to boost acetylcholine levels in the brain.
Alzheimer's disease is also somewhat hereditary, as certain forms, particularly early onset Alzheimer's disease, are caused by mutations in specific genes, with less than five percent of patients having this form. Additionally, the presence of certain genetic variants, such as the apolipoprotein E (APOE) E4 allele, increases the likelihood of developing AD. However, the statement that most forms of AD are hereditary is not accurate; most cases are sporadic with no known direct cause, although there is a genetic component to the risk.
Opiate exposure as a cause of AD, and the notion that the disease is congenital, are not true according to current scientific understanding. While opiates are not identified as a cause of Alzheimer's, there may be connections to lifestyle factors such as smoking, obesity, and cardiovascular health. Congenital implies the disease is present from birth; however, Alzheimer's is a progressive disease typically manifesting in older adults, although rare cases can occur earlier due to genetic factors.