69.4k views
1 vote
The endosteum is a region of the bone marrow where __________

a) immature B cells are exported to the circulation
b) small pre-b cells initiate the rearrangement of light-chain genes
c) a high proportion of hematopoietic stem cells reside
d) late pro-b cells accumulate while completeing rearrangement of heavy-chain genes

User Vidi
by
8.0k points

1 Answer

2 votes

Final answer:

The endosteum is a region of the bone marrow where a high proportion of hematopoietic stem cells reside, which are essential for the production of various types of blood cells including B cells that mature in the bone marrow.

Step-by-step explanation:

The endosteum is a region of the bone marrow where a high proportion of hematopoietic stem cells reside. The red bone marrow is where hematopoiesis, the process of blood cell production, including B cells, occurs.

Throughout this process, hematopoietic stem cells differentiate into various cell types, including the myeloid lineage that gives rise to erythrocytes and leukocytes and the lymphoid lineage that further develops into B cells within the bone marrow or T cells in the thymus gland. While B cells mature almost entirely in the red bone marrow, T cells, or thymocytes, leave the marrow and continue their maturation in the thymus.

User Kurdtc
by
8.5k points
Welcome to QAmmunity.org, where you can ask questions and receive answers from other members of our community.