Final answer:
Rett Syndrome is primarily an X-linked dominant disorder affecting mainly females, where the mutation on one of the X chromosomes is sufficient to cause the disorder.
Step-by-step explanation:
Rett Syndrome is a genetic neurological disorder characterized by a period of normal development followed by a loss of motor and cognitive skills. It's primarily observed in females and is caused by mutations on the X chromosome. Regarding the inheritance pattern of Rett Syndrome, it is not autosomal dominant, autosomal recessive, or X-linked recessive, but is typically considered an X-linked dominant condition. This means the mutation causing Rett Syndrome is located on the X chromosome, and one copy of the mutated gene is enough to cause the disorder in females (XX), while it is often lethal in males (XY), who have only one X chromosome. In contrast, autosomal dominant disorders like Huntington's disease require only one mutant allele to express the disorder, and an individual with such a disorder has at least one faulty gene. Likewise, autosomal recessive disorders like cystic fibrosis require two copies of the recessive allele for the disease to be expressed.