Answer:
To answer your question, the Enzyme-substrate complex (ES) has stronger non-covalent interactions compared to the transition state (EX). This is because the ES complex is a more stable and specific interaction between the enzyme and the substrate, which is essential for the catalytic process.
The non-covalent interactions in the ES complex include hydrogen bonding, ionic interactions, van der Waals forces, and hydrophobic forces, which are all stronger than the non-covalent interactions in the transition state. These interactions help to stabilize the ES complex and facilitate the reaction.
Step-by-step explanation: