The correct answer is the following: option 4. "With cares and fears ne'er cumb'red be" is the line in the excerpt from "As Weary Pilgrim, Now at Rest" that best demonstrates the speaker's desire to be free from the burdens of the world. The line reflects on how the speaker will never be burdened or hindered by fear or cares, to demonstrate her desire to be free from all of the conflict and darkness of the world. These lines add to the main theme of the poem written by Anne Bradstreet, that is the discussion of death, and how death can sometimes be seen as an alleviation from any type of sorrow the world can throw at you. Breadstreet reflects upon this when encountering a loved one passing away after dealing with a lot of pain and sorrow.