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Why does the enzyme pepsin (present in the stomach) denature in the intestine?

The enzyme denatures due to change in temperature as it enters the intestine.
The enzyme denatures due to the alkaline environment of the intestine.
The enzyme denatures due to lack of substrate molecules in the intestine.

User MBardos
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2 Answers

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Ans : The enzyme denatures due to the alkaline environment in the intestine as enzyme pepsin works best in acidic ph and the extreme change in ph will cause it to denature
User Mike DaCosta
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I think the correct answer from the choices listed above is the second option. The enzyme pepsin (present in the stomach) denature in the intestine due to the alkaline environment of the intestine. Pepsin works at an acidic pH. Hope this answers the question. Have a nice day.
User Reverend Pete
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