Answer: True
In Act 1, Scene 3 of Hamlet, we see Ophelia and her family. Laertes is preparing to go to France, and Ophelia has come to say goodbye. He asks her about Hamlet, and advises her not to fall in love with him, as it is unlikely that he will be able to marry her. Polonius walks in afterwards, and similarly advises her to ignore Hamlet. However, we do not see Ophelia's mother, nor is she referenced by anyone.