The correct answer to this open question is the following.
The American leader that best exemplified the Enlightenment through his scientific discoveries and inventions is Benjamin Franklin.
Benjamin Franklin was a prominent American that signed the Declaration of Independence on July 4, 1776, and was one of the founding fathers of the United States. He also was an inventor. Among his most important inventions, we have the bifocal lens, the lightning rod, the glass harmonica, and the stove.