Below is a list of the several causes of runtime error 1921.
1. Incomplete or corrupt download of TurboTax software.
2. Virus infection that has corrupted Turbo or windows system files.
3. Another program mistakenly deleted TurboTax-related files.
4. Corruption in windows registry.
Error 1921 can be caused by other factors. Therefore, it is recommended to run a troubleshooting procedure for each of the possible causes. In addition, you can close all running programs including TurboTax and restart your computer. This will probably fix the error.