Question

Neurofibromatosis, a genetic disease caused by mutation on the NF1 gene, follows an autosomal dominant pattern of inheritance. The diagram shows that the father carries two copies of the defective gene and the mother is unaffected. What percentage of offspring will have neurofibromatosis?

Affected: RR Normal: rr


A: 0%

B: 25%

C: 50%

D: 100%

Answer 1

100% is the correct answer

Step-by-step explanation:

Answer 2

As you can see in a cross shown in the image below, all of the progeny would have the Rr genotype.
Since the NF1 gene that is the genetic causes of Neurofibromatosis is expressing an autosomal dominant pattern of inheritance, the heterozygotes would also have the disease.
Therefore, the correct answer is D, 100%.