Question

The HMGR-3 allele fails to bind with SREBP. The portion of the gene that is broken in this allele is the

Answer 1

Out of the following given choices;

Allosteric site

Active site

Regulatory region

Coding region

The answer is Regulatory region. This region controls the activity of catalytic domain. HMGR-3 codes for the HMG-CoA reductase significant in cholesterol metabolism. SREBP binds to the gene regulatory region. The protein promotes transcription of the gene.