Question

What are the H-bonds in Fentanyl, and is it souluable in water please explain yes or no.

Answer 1

There are no H-bonds in fentanyl, and it is not soluble in water.

Step-by-step explanation:

Pure fentanyl has no hydrogen bonds, because it has no H atoms bonded to O or N.

Water can H-bond to the carbonyl O atom of the amide and to the N atom of the 3° amine in the piperidine ring.

However, these attractive forces are swamped by the nonpolar hydrophobic character of the benzene and piperidine rings.

As a result, Fentanyl is insoluble in water. Its solubility is only 20 mg/100 mL water.

Answer 2

Fentanyl is an opoid used for the pain medication together with other medications for anesthesia. It is illegally used as recreation drug as it is mixed with heroine and cocaine. The side effects of this fentanyl include vomiting, constipation, sedation, decreased breathing, hallucinations etc. Fentanyl does not have any hydrogen bonds instead it has nitrogen bonds associated with benzene ring. It does not form molecules within its molecules but forms hydrogen bonds with the water molecule. The nitrogen and the oxygen present forms bonds with the hydrogen of the water molecule. As it forms hydrogen bonds with water it is soluble in water.