Answer:
They first enslaved Native Americans.
Step-by-step explanation:
In general, throughout America, Native Americans were enslaved first. However, this practice was generally abandoned for two main reasons. First, in the Spanish colonies, the Spanish Crown recognized all Native Americans as subjects of the Crown. This meant that they could not legally be enslaved. The second, and perhaps more important reason, was the fact that many Native Americans died after colonization due to war and diseases they had no resistance to. This meant that there were not enough Native Americans to fulfill the labor requirements of the Europeans.