Question

why is tetracycline selectively toxic against bacteria Eukaryotic cells will enzymatically destroy the drug. Eukaryotic cells will actively pump the drug out of their interiors. The drug affects peptidoglycan synthesis, and eukaryotic cells have no peptidoglycan. The drug binds to the 30S small ribosomal subunit — eukaryotes have a 40S small subunit. Eukaryotes lack a small ribosomal subunit, so the drug cannot negatively affect them.

Answer 1

The correct answer is The drug binds to the 30S small ribosomal subunit eukaryotes have 40S small sub unit.

Step-by-step explanation:

Tetracycline belongs to broad spectrum antibiotic.Tetracycline is named so because it contain a derivative of four hydrocarbon rings.

Tetracycline act by inhibiting the protein synthesis process in prokatotes by binding to the small ribosomal subunit also called 30S subsunit and blocks the binding of amino acyl tRNA to the A site or attachment site of ribosome.

As eukaryotes contain 40S ribosomal subunit,it becomes difficult for tetracycline to bind with 40S ribosomal subunit of eukaryotes.