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Which is more stable, a trans-1,4-disubstitutedcyclohexane or
its cis isomer?

User Houdmont
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1 Answer

3 votes

Answer:

If the substituents are the same, the cis distribution is more stable than trans distribution.

Step-by-step explanation:

A cis cyclohexane is one in which both substituents are oriented towards the same face of the ring regardless of the conformation.

A trans cyclohexane has substituents on opposite sides of the ring.

In trans-1,4-disubstituted cyclohexane, the conformation with the two substituent groups in equatorial is more stable than the constitution that has the axial groups.

In cis-1,4-disubstituted cyclohexane, both conformations have the same stability as they have an axial and an equatorial substituent, so they have the same energy and there is no equilibrium shift.

Which is more stable, a trans-1,4-disubstitutedcyclohexane or its cis isomer?-example-1
User Magofoco
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