Answer: 2399760
Explanation:
The concept we use here is Partial derangement.
It says that for m things , the number of ways to arrange them such that k things are not in their fixed position is given by :-

Given digits : 0,1,2,3,4,5,6,7,8,9
Prime numbers = 2,3,5,7
Now by Partial derangement the number of ways to arrange 10 numbers such that none of 4 prime numbers is in its original position will be :_

Hence, the number of ways can the digits 0,1,2,3,4,5,6,7,8,9 be arranged so that no prime number is in its original position = 2399760