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How are the major blood groups determined?

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Human blood type is determined by the presence or absence of certain identifiers on the surface of red blood cells. ... There are four main ABO blood type groupings: A, B, AB, and O. These blood groups are determined by the antigen on the blood cell surface and the antibodies present in the blood plasma.
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There are four main ABO blood type groupings: A, B, AB, and O.

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