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How did the pioneers significantly affect Native Americans? Settlers refused to help American Indians find better sources of water. Settlers helped American Indians preserve native plants and animals.
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How did the pioneers significantly affect Native Americans?

Settlers refused to help American Indians find better sources of water.

Settlers helped American Indians preserve native plants and animals.

Settlers spread diseases that killed thousands of American Indians.

Settlers adopted some of the customs of American Indians.

User Greg Robertson
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Answer:

Settlers spread diseases that killed thousands of Native Americans.

Step-by-step explanation:

User Papa Kojo
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settlers spread diseases

User Jitendra Varshney
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