Answer: Receptors would be unable to return to their inactive form and respond to new signals.
Step-by-step explanation:
Many signaling pathway involves the regulation of the protein synthesis. It involves the turning off or on of some of the specific genes present in the nucleus. If the receptors become unable to resume to the inactive form the may not be able to produce new signals during protein synthesis. The final activated molecule in a signal pathway may not function as transcription factor.