Question

In the analysis of quantitative traits, positions on chromosomes called quantitative trait loci (QTLs) are often discussed. In the same context, restriction fragment length polymorphisms (RFLPs) are also discussed. What is the relationship between QTLs and RFLPs

Answer 1

RFLP technique can be used to develop useful polymorphic molecular markers for mapping QTLs.

Step-by-step explanation:

A quantitative trait locus (QTL) is a fragment of DNA whose variation is associated with phenotypic traits controlled by numerous genes (i.e., quantitative traits) such as, for example, height, weight, etc. Restriction fragment length polymorphism (RFLP) is a technique useful to detect DNA polymorphisms (i.e., genetic variation) among samples. In RFLP, the genome is digested using restriction enzymes and these restriction fragments are subsequently separated by electrophoresis depending on their size, thereby producing differential gel bands among samples. These polymorphisms can be used to map QTLs and develop linkage maps, which is known as RFLP mapping.