Question

Calculate the carboplatin dose for a 60 year old man patient weighing 200 pounds. the patient's serum creatinine is 1.2mg/dL with a target AUC of 6.

a)655mg
b)505mg
c)578 mg
d)530 mg

Answer 1

Given :

Calculate the carboplatin dose for a 60 year old man patient weighing 200 pounds.

The patient's serum creatinine is 1.2mg/dL with a target AUC of 6.

To Find :

The carboplatin dose.

Solution :

Carboplatin dose is given by :

`C.D = AUC* [((140-age)* ( weight \ in \ pounds))/(serum \ creatinine(mg/dL)*7.2* 2.2)+25]`

Putting all given values in above equation, we get :

`C.D = 6* [(((140-60)* ( 200))/(1.2*72* 2.2))+25]\\\\C.D =655.05\ mg`

Therefore, the carboplatin dose is 655.05 mg.