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In a series of experiments , Griffith infected mice with nonvirulent R -strain bacteria and highly virulent S -strain bacteria . Heat -killed S bacteria were nonvirulent . However , the nonvirulent heat -killed bacteria and the nonvirulent R bacteria together produced a virulent mixture . What did this demonstrate ? A. A transforming principle in the bacteria allowed the nonvirulent R strain to become virulent . B. The molecules present on the outside of bacteria determine whether it's virulent or nonvirulent . C. The S -strain bacteria had not been killed completely . D. The translation of proteins , carbohydrates , lipids , and DNA is important in determining bacterial virulence .

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Answer:

A transforming principle in the S bacteria allowed the nonvirulent R-strain to become virulent.

Reference:

3.2 Examine the structure of DNA and its function with genetic inheritance

DNA's Structure and Function in Genetic Inheritance READING ASSIGNMENT

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"...the combination of the heat-killed S-strain and the nonvirulent R-strain caused a 'bacterial transformation,' which rendered the combination highly virulent and fatal to the mouse." (PDF pg. 44)

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