Answer:
a) norepinephrine, serotonin
Step-by-step explanation:
Neurotransmitters are special lipid-based molecules used in chemical signal transduction in the nervous system. They have receptor-specific roles in activating different regions of the central nervous system (CNS) and physiological responses. These include: dopamine, norepinephrine, and serotonin .
The CNS, which includes the brain and spinal cord, can be affected by certain drugs like methamphetamine. This drug is a stimulant that acts on brain regions such as:
- prefrontal cortex
- the striatum
- the nucleus accumbens
It causes the release of neurotransmitters while blocking their reuptake at synapses; meth is metabolized very slowly over time (12 hours). The buildup of dopamine, for instance, leads to altered moods, feelings of pleasure and euphoria.
Thus, this change or "high" leads to dependency by users for its mood-altering effect; however, less dopamine is released, and the pleasurable effects, become less potent. Studies show neurological damage with prolonged use, and habit formation and over time, addiction.