Answer:
Pilocarpine can affect the heart since it shares the drug's binding site with the traditional receptors that it seeks to effect under treatments of xerestomia, dry eyes or Sjorgen's syndrome.
Step-by-step explanation:
The effect is Parasympathomimetic in the exocrine glands, but these glands have the same receptors as the cardiac tissue, so you can see harmful cardiac side effects.
It increases adverse effects with ß-adrenergic antagonists, thus generating heart failure, and even kidney failure indirectly due to the possible risk of chronic heart failure.