Final answer:
The statement 'Caffeine is the most addictive of all drugs' is not supported by the provided passages and should not be included in the summary, as the passages describe caffeine as less potent compared to other stimulants.
Step-by-step explanation:
Among the statements provided, the statement that should NOT be included in a summary of Passage 2 is "Caffeine is the most addictive of all drugs." This statement is factually incorrect based on the provided material. While caffeine is indeed a widely consumed psychoactive substance and its use can lead to tolerance and some level of physical or mental dependence, it is not characterized as the most addictive when compared to other drugs such as cocaine. In the context of the passages, caffeine's primary action is its antagonism of adenosine receptors which affects alertness and arousal, and while it is mentioned to potentially have negative health effects and reactions with some medications, its categorization as the most addictive substance is not supported. Furthermore, the text does mention the inclusion of caffeine in some medical applications, thus acknowledging that medications can react with caffeine, and it also recognizes that certain individuals may experience negative health effects from caffeine consumption.