Answer:
Its location on the sea made it a cultural crossroads.
Step-by-step explanation:
The first option is the correct one because Alexander built the city on this place due to a fact that it enabled him to connect different parts of the Empire. It was a crossroad of trade, knowledge and culture and for a long time the center of Mediterranean.
Second option is not correct as during Hellenistic period Greece was not as important as it was during previous eras, especially classical period.
Third option is not correct as Alexandria is located in Africa.
Fourth option is not correct as Egypt is and was a global center and a crossroad.