Answer:
A is wrong, because that fact just simply is not true. There have been several other raced men and some women as well that made important contributions to science.
B is correct, because science isn't attributable to just the last couple of hundred years. In ancient times, people developed astronomy and medicine. This is also correct because it names females as part of the scientific contributions to society.
C is incorrect, because this fact is also completely false. Lots of important scientific discoveries have been made from before that, such as the invention of electricity (somewhat useful today I would guess:\) in 1879, which is much longer than 100 years ago.
D is also incorrect, because scientific knowledge is changing constantly, every minute, growing and expanding and changing to accomodate new knowledge and information that we've discovered.