Question

Dinitrophenol (2,4-DNP) destroys proton gradients without affecting anything else about a membrane. Its pKa slightly acidic, so it can be protonated or unprotonated in cells.a. What would be the effect of adding dinitrophenol to the mitochondrial inner membrane

Answer 1

the effect of adding dinitrophenol to the mitochondrial inner membrane is -:

• Production of ATP
• No electron transfer
• production of more sugar as energy
• Uncoupling of ETC(electron transport chain)

Step-by-step explanation:

Dinitrophenol is an uncoupler which can isolate the progression of electrons and siphoning of H+ particles for ATP Synthesis. On adding the dinitrophenol, the energy from the electron move can't be utilized for ATP blend. It has been utilized in diet pills and as a counting calories help. It goes about as protonophore and permits spillage of the protons through the internal mitochondrial layer which subsequently sidesteps ATP synthase and consequently the creation of ATP creation gets wasteful. It hinders the ATP synthase and thus its capacity to deliver ATP. It likewise influences the ETC in light of the fact that forestalls development of electrons over the ETC. Uncoupling the ETC would prompt diminished ATP creation and consequently increasingly more sugar is used as energy. This would restrict accessibility of ATP and make a deadly circumstance.