Answer:
C. It led to Spanish being spoken by half the population of region
Step-by-step explanation:
Given that Western Hemisphere covers both North and South America, the long-term effect that Spanish colonization has on the Western Hemisphere is that "It led to Spanish being spoken by half the population of the region" This is evident when about 18 countries and one territory in America speaks Spanish as their official language.
Option A is wrong because Canada uses both English and French for road signs.
Option B is wrong because Portuguese is used in Brazil
Option D is wrong because English is the largest speaking population in the United States