A - B is the complement of B in A; in other words, all the elements of A that do not belong to B.
Since A ∩ B = {4, 6}, we have
A - B = {2, 8, 10}
Then the complement of A - B, denoted (A - B)' is all the elements of the universal set U that do not belong to A - B.
(A - B)' = {1, 3, 4, 5, 6, 7, 9}