The Spanish explorer Francisco Pizarro invaded the Incan Empire in 1532, seeking riches. The Inca had already had some contact with Europeans, and many had died of European diseases. The empire was also weakened by a civil war between two ruling brothers. Pizarro manipulated the two sides, eventually defeating both. He ended the Incan Empire.
After a three-month siege, Spanish forces under Hernán Cortés capture Tenochtitlán, the capital of the Aztec empire. Cortés' men leveled the city and captured Cuauhtémoc, the Aztec emperor. He ended the Aztec Empire.